Identification of differential expression of genes in hepatocellular carcinoma by suppression subtractive hybridization combined cDNA microarray

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Identification of differential expression of genes in hepatocellular carcinoma by suppression subtractive hybridization combined cDNA microarray.

The genetic background of hepatocellular carcinoma (HCC) has yet to be completely understood. Here, we describe the application of suppression subtractive hybridization (SSH) coupled with cDNA microarray analysis for the isolation and identification of differential expression of genes in HCC. Twenty-six known genes were validated as up-regulated and 19 known genes as down-regulated in HCC. The ...

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ژورنال

عنوان ژورنال: Oncology Reports

سال: 2007

ISSN: 1021-335X,1791-2431

DOI: 10.3892/or.18.4.943